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What is 1-(2-Diphenyl)piperazine?

  • It is a selective antagonist at the 5HT7 serotonin receptor.
  • IUPAC Name: 1-(2-phenylphenyl)piperazine
  • InChI: InChI=1S/C16H18N2/c1-2-6-14(7-3-1)15-8-4-5-9-16(15)18-12-10-17-11-13-18/h1-9,17H,10-13H2
  • Canonical SMILES: C1CN(CCN1)C2=CC=CC=C2C3=CC=CC=C3
  • Molecular formula: C16H18N2
  • Molecular weight: 238.33 g·mol−1
  • Synonyms:
  1. 1-(biphenyl-2-yl) piperazine
  2. 180698-18-4
  3. 1-(biphenyl-2-yl)piperazine
  4. CHEMBL494675
  5. 1-(2-Biphenyl)piperazine 2HCl
  6. 1-([1,1'-Biphenyl]-2-yl)piperazine
  7. 1-(2-phenylphenyl)piperazine
  8. 1-biphenyl-2-yl-piperazine
  9. SCHEMBL3759275
  10. ZINC2243427
  11. BDBM50395191
  12. AKOS009159321
  13. HG-0209
  14. Q4545723



  1. National Center for Biotechnology Information (2021). PubChem Compound Summary for CID 2737389, 1-(Biphenyl-2-yl) piperazine. Retrieved July 29, 2021 from https://pubchem.ncbi.nlm.nih.gov/compound/1-_Biphenyl-2-yl_-piperazine.

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