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What is 1-Methyl-3-propyl-4-(p-chlorophenyl)piperidine?

1-Methyl-3-propyl-4-(p-chlorophenyl)piperidine structure
  • It is a potent dopamine reuptake inhibitor.
  • IUPAC Name: (3S,4S)-4-(4-chlorophenyl)-1-methyl-3-propylpiperidine
  • InChI: InChI=1S/C15H22ClN/c1-3-4-13-11-17(2)10-9-15(13)12-5-7-14(16)8-6-12/h5-8,13,15H,3-4,9-11H2,1-2H3/t13-,15-/m1/s1
  • Canonical SMILES: CCCC1CN(CCC1C2=CC=C(C=C2)Cl)C
  • Isomeric SMILES: CCC[[email protected]@H]1CN(CC[[email protected]@H]1C2=CC=C(C=C2)Cl)C
  • Molecular formula: C15H22ClN
  • Molecular weight: 251.79 g·mol−1
  • Synonyms:
  1. CHEMBL109097
  2. SCHEMBL3832400
  3. BDBM50082395
  4. (3S,4S)-4-(4-Chlorophenyl)-1-methyl-3-propylpiperidine
  5. (3S,4S)-4-(4-Chloro-phenyl)-1-methyl-3-propyl-piperidine
  6. 214335-23-6


What are the uses of this drug?

It is a potential therapeutic agent for the treatment of cocaine addiction.[2]


  1. National Center for Biotechnology Information (2021). PubChem Compound Summary for CID 9837874. Retrieved July 31, 2021 from https://pubchem.ncbi.nlm.nih.gov/compound/9837874.
  2. US 6180648, Kozikowski AP, Araldi GL, "Analogs of cocaine", issued 2001-01-30 

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