18F-EF5
18F-EF5
18F-EF5 (pronounced "eighteen F E F five") is a radiopharmaceutical used in Positron Emission Tomography (PET) imaging to measure hypoxia (low oxygen levels) in tissues, particularly in the context of cancer research and treatment.
Etymology
The term 18F-EF5 is derived from the chemical composition of the compound. The "18F" refers to Fluorine-18, a radioactive isotope of fluorine used in PET imaging. "EF5" is an abbreviation for 2-(2-nitro-1H-imidazol-1-yl)-N-(2,2,3,3,3-pentafluoropropyl)acetamide, the chemical name of the compound.
Usage
18F-EF5 is used in PET imaging to detect hypoxic regions in tissues. Hypoxia is a common characteristic of many types of cancer, and the ability to accurately measure and map hypoxic regions can be crucial in cancer research and treatment planning. The compound is injected into the patient's bloodstream, where it travels to areas of hypoxia and binds to cellular proteins. The radioactive decay of the Fluorine-18 isotope can then be detected by the PET scanner, allowing for the visualization of hypoxic regions.
Related Terms
- Radiopharmaceutical
- Positron Emission Tomography
- Hypoxia
- Cancer
- Fluorine-18
- 2-(2-nitro-1H-imidazol-1-yl)-N-(2,2,3,3,3-pentafluoropropyl)acetamide
External links
- Medical encyclopedia article on 18F-EF5
- Wikipedia's article - 18F-EF5
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