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18f 6f dopamine

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18f 6f dopamine - a radioconjugate consisting of 6 fluorodopamine labeled with fluorine f18 (6 18ffda), with potential diagnostic activity. Upon administration, 6 18ffda is taken up by presynaptic sympathetic nerve endings via the norepinephrine transporter (net) uptake 1. Once inside, 6 18ffda is rapidly converted by dopamine beta hydroxylase into 6 18ffluoronorepinephrine (6 18ffne) and stored into neuronal storage vesicles. Upon positron emission tomographic (pet) scanning of the f18, sympathetic innervated regions can be visualized, such as those in pheochromocytoma.

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Source: Data courtesy of the U.S. National Library of Medicine. Since the data might have changed, please query MeSH on 18f 6f dopamine for any updates.

 

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