18fspa rq - a radioconjugate consisting of the positron emitting radioisotope fluorine f 18 conjugated to the substance p antagonist receptor quantifier (spa rq) used in radioimaging. 18f labeled substance p antagonist receptor quantifier is an antagonist of the neurokinin 1 (substance p) receptor (nk1r) and can function as a positron emission tomography (pet) imaging agent for detecting nk1r expressing cells and tissues. Nk1rs are frequently expressed on the plasma membranes of tumor cells from glioblastoma and breast and pancreatic carcinomas.
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