2-hydroxyestrogens - any metabolite formed during the catabolism of estrogens by the liver through the hydroxylation of the carbon at position 2 by various cytochrome p450 (cyp) enzymes, including cyp3a4, 1a1 and 1a2. The 2-hydroxyestrogens have minimal estrogenic activity compared to the parent compounds. Also see 2-hydroxyestrogen
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Source: Data courtesy of the U.S. National Library of Medicine. Since the data might have changed, please query MeSH on 2-hydroxyestrogens for any updates.