WikiMD is world's largest health encyclopedia with
28,546 pages, 3,991,519 edits & 34,308,805 views.
2-hydroxyflutamide depot
A depot formulation containing a bioresorbable, controlled-release, calcium sulphate-based paste of the nonsteroidal antiandrogen 2-hydroxyflutamide (2-HOF) with potential antineoplastic activity. Upon injection into the tumor site in the prostate, 2-hydroxyflutamide depot slowly releases 2-HOF, which competitively binds to androgen receptors (ARs), blocking the binding of dihydrotestosterone (DHT). This may inhibit androgen-dependent DNA and protein synthesis, resulting in tumor cell growth arrest and decreased cellular proliferation. In addition, 2-HOF inhibits nuclear uptake of androgen in androgen-responsive tissues.
Learn more about 2-hydroxyflutamide depot
Latest research (Pubmed)
External links
WikiMD needs you!
This WikiMD article 2-hydroxyflutamide depot is a stub.
If you are a healthcare professional familiar with the topic 2-hydroxyflutamide depot, or
A subject matter expert or authority on 2-hydroxyflutamide depot, you can help us.
About | Mission | Paid editors welcome!
| 2-hydroxyflutamide depot is part of WikiMD's Physician reviewed^ articles available 4free, 4all, 4ever! |
|---|
| Medicine: Health - Encyclopedia - Topics - Diseases - Cancer - Rare diseases - Random Page Navigation: Drugs - Wellness - Obesity - Diet - Ketogenic diet - W8MD weight loss diet - Editors: Recently Edited Pages - Alphabetical Order - Sponsors - USMLE The content on or accessible through WikiMD is for informational purposes only. WikiMD is not a substitute for professional medical advice. ^See full Disclaimers |
 Ad. Tired of being overweight?. W8MD's insurance Weight loss program can HELP* |
