doctor


W8MD Diet | COVID-19 portal | Vitamin D | Vaccine | Keto

WikiMD is the world's largest medical encyclopedia with
290,644 pages, 4,287,074 edits & 44,326,849 views.

Free unbiased diet, health and wellness info!

3,4-methylenedioxymethamphetamine

From WikiMD's free health, diet & wellness encyclopedia
Jump to navigation Jump to search

A ring-substituted amphetamine derivative, structurally related to the hallucinogen mescaline, with entactogenic, neurotoxic, and motor-stimulatory activities. 3,4-methylenedioxymethamphetamine (MDMA) produces an acute, rapid enhancement in both the release of serotonin from and the inhibition of serotonin reuptake by serotonergic nerve endings in the brain. Once within the cell, MDMA depletes stores of tryptophan hydroxylase (TPH) via acute oxidative inactivation; in turn, depleted stores of TPH leave cell terminals open to damage from oxidative stress, possibly a source of MDMA neurotoxicity. This agent also induces norepinephrine, dopamine, and acetylcholine release and can act directly on a number of receptors, including alpha 2-adrenergic and 5-hydroxytryptamine (5-HT) 2A receptors. MDMA may suppress the dyskinesia associated with long-term use of L-dopamine (L-DOPA) without affecting the efficacy of L-DOPA treatment.

Learn more about 3,4-methylenedioxymethamphetamine

Latest research - 3,4-methylenedioxymethamphetamine

PubMed
Clinical trials

External links

Wikipedia
Medicine icon
Medicine icon

This WikiMD article 3,4-methylenedioxymethamphetamine is a stub. If you are familiar with the topic 3,4-methylenedioxymethamphetamine, you can help us. Paid editors welcome!

 

3,4-methylenedioxymethamphetamine is part of WikiMD's free ^articles!

^3,4-methylenedioxymethamphetamine (article) is provided for informational purposes only. No expressed or implied warranties as to the validity of content.
WikiMD is not a substitute for professional advice. By accessing and using WikiMD you agree to the terms of use.
Templates etc. when imported from Wikipedia, are licensed under CC BY-SA 3.0. See full disclaimers.
W8MD weight loss logo

Ad. Tired of being overweight?. W8MD's physician weight loss program can HELP. Tele medicine available