5-hydroxytryptamine

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5-Hydroxytryptamine

5-Hydroxytryptamine (pronounced: five-hy-drox-y-trip-ta-mine), also known as serotonin, is a neurotransmitter that plays a significant role in the regulation of mood, appetite, and sleep.

Etymology

The term "5-Hydroxytryptamine" is derived from its chemical structure, which consists of an indole ring that is hydroxylated at the 5th position, and a side chain amine. The term "serotonin" is derived from its discovery when it was found to be a vasoconstrictor in serum, hence "sero-" for serum and "-tonin" for tone.

Function

5-Hydroxytryptamine is produced in the brain and the intestines. In the brain, it is involved in the regulation of various functions such as mood, appetite, and sleep. In the intestines, it regulates intestinal movements.

Related Terms

  • Neurotransmitter: A chemical substance that is released at the end of a nerve fiber by the arrival of a nerve impulse and, by diffusing across the synapse or junction, causes the transfer of the impulse to another nerve fiber, a muscle fiber, or some other structure.
  • Brain: The organ of the body which controls all functions, interpreting sensory information and coordinating body activities.
  • Indole: A heterocyclic aromatic organic compound that has been found in certain essential oils.
  • Amine: Any of a class of compounds derived from ammonia by replacement of one or more hydrogen atoms with organic groups.

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