8-Aminoquinoline

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8-Aminoquinoline

8-Aminoquinoline (pronunciation: 8-ah-mee-no-kwin-o-leen) is a type of quinoline, which is a class of organic compounds. It is used as a base structure in medicinal chemistry to synthesize drugs with antimalarial and antiparasitic properties.

Etymology

The term "8-Aminoquinoline" is derived from its chemical structure. The "quinoline" part of the name refers to the type of organic compound it is, while the "8-Amino" part refers to the presence of an amino group at the 8th position of the quinoline structure.

Related Terms

  • Quinoline: A class of organic compounds that 8-Aminoquinoline belongs to.
  • Amino group: A functional group that consists of a nitrogen atom attached by single bonds to hydrogen atoms, alkyl groups, aryl groups, or a combination of these three.
  • Antimalarial drugs: A type of medication used in the prevention and treatment of malaria, a disease caused by parasites that enter the body through the bite of a mosquito.
  • Antiparasitic drugs: Medications used to treat infections caused by parasites.

Uses

8-Aminoquinoline compounds are primarily used in the synthesis of antimalarial and antiparasitic drugs. They are known for their ability to kill the dormant liver stage of the malaria parasite, which most antimalarial drugs cannot do. This makes them particularly useful in the prevention of relapses in patients with malaria.

See Also

  • Primaquine: An 8-Aminoquinoline drug used to prevent and treat malaria.
  • Tafenoquine: Another 8-Aminoquinoline drug used for the same purpose.

External links

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