Doctor in scrubs

W8MD Diet | COVID-19 portal | Vitamin D | Vaccine | Keto

WikiMD is the world's largest medical encyclopedia with
13,990 pages, 4,158,316 edits & 43,278,125 views.

Free unbiased diet, health and wellness info!


From WikiMD's free health, diet & wellness encyclopedia
Jump to navigation Jump to search

89zr-dfo-fianlimab - a radioimmunoconjugate consisting of fianlimab, a human monoclonal antibody directed against the inhibitory receptor lymphocyte activation gene-3 protein (lag-3; lag3; cd223), linked, via the chelator desferrioxamine (dfo), to the positron-emitting radionuclide zirconium zr 89 (zr89), with potential use as an imaging agent upon positron emission tomography (pet) imaging. Upon administration of zirconium zr 89-dfo- fianlimab, the fianlimab moiety specifically targets and binds to lag-3. Upon binding, the radioisotope moiety may be detected using pet, thereby allowing the imaging and quantification of lag-3-expressing tumor infiltrating lymphocytes (tils). Lag-3, a member of the immunoglobulin superfamily (igsf), is expressed on various immune cells; its expression on tils is associated with tumor-mediated immune suppression and the negative regulation of both cellular proliferation and t-cell activation. Also see zirconium zr 89-dfo-fianlimab

Up to date info


Latest research - 89zr-dfo-fianlimab

Clinical trials

Source: Data courtesy of the U.S. National Library of Medicine. Since the data might have changed, please query MeSH on 89zr-dfo-fianlimab for any updates.


89zr-dfo-fianlimab is part of WikiMD's free ^articles!

^89zr-dfo-fianlimab (article) is provided for informational purposes only. No expressed or implied warranties as to the validity of content.
WikiMD is not a substitute for professional advice. By accessing and using WikiMD you agree to the terms of use.
Templates etc. when imported from Wikipedia, are licensed under CC BY-SA 3.0. See full disclaimers.
W8MD weight loss logo

Ad. Tired of being overweight?. W8MD's physician weight loss program can HELP. Tele medicine available