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9h purine 6thio 98d

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 - an antimetabolite analogue of purine with antineoplastic and immuno suppressant properties. 9h purine 6thio 98d substitutes for the normal nucleoside and fraudulently incorporates into dna and inhibits de novo purine synthesis, thereby inducing cell death. In vivo, this agent, also known as 6mp arabinoside, may occur as a metabolite of the antineoplastic agent mercaptopurine. (nci04)

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Source: Data courtesy of the U.S. National Library of Medicine. Since the data might have changed, please query MeSH on 9h purine 6thio 98d for any updates.


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