A-349,821
A-349,821
A-349,821 (/eɪ-ˈθriː-ˈfɔːr-ˈnaɪn-ˈeɪt-ˈtwɛnti-wʌn/) is a potent and selective agonist of the human alpha-2 adrenergic receptor subtype α2C. It is used in scientific research and has been studied for potential therapeutic applications.
Etymology
The term "A-349,821" is a systematic name derived from the compound's development sequence in the laboratory. The "A" signifies the first series of compounds, and "349,821" is the specific number assigned to this compound.
Pharmacology
A-349,821 acts as an agonist at the α2C adrenergic receptor, a type of G protein-coupled receptor (GPCR) that is activated by the neurotransmitter norepinephrine. By selectively activating this receptor subtype, A-349,821 can modulate the function of certain neurons in the brain and peripheral nervous system.
Therapeutic Potential
Research has suggested that α2C adrenergic receptor agonists like A-349,821 may have potential therapeutic applications in conditions such as depression, anxiety disorders, and certain types of pain. However, further research is needed to fully understand the potential benefits and risks of these compounds.
Related Terms
- Agonist
- Alpha-2 adrenergic receptor
- G protein-coupled receptor
- Norepinephrine
- Depression
- Anxiety disorders
- Pain
External links
- Medical encyclopedia article on A-349,821
- Wikipedia's article - A-349,821
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