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Information about Methocarbamol

Methocarbamol is a commonly used, centrally acting muscle relaxant and has not been linked to instances of liver injury.

Mechanism of action of Methocarbamol

Methocarbamol (meth" oh kar' ba mol) is a guaifenesin derivative and acts centrally as a muscle relaxant by an unknown mechanism.  Methocarbamol was approved for use in the United States in 1957, and currently more than 3 million prescriptions are filled yearly. 

Clinical use of Methocarbamol

Methocarbamol is indicated for the relief of acute, painful musculoskeletal conditions. 

Dosage and administration for Methocarbamol

Methocarbamol is available in 500 and 750 mg tablets in several generic formulations, both alone and in combination with other drugs and under the brand names of Robaxin and Marbaxin.  The recommended dosage is 1500 mg orally three to four times daily. 

Side effects of Methocarbamol

The most common side effects of methocarbamol are drowsiness blurred vision, headache, nausea and skin rash.

Muscle relaxants

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