Doctor in scrubs


W8MD Diet | COVID-19 portal | Vitamin D | Vaccine | Keto

WikiMD is the world's largest medical encyclopedia with
312,668 pages, 4,239,227 edits & 44,166,673 views.

Free unbiased diet, health and wellness info!

AZD2281

From WikiMD's free health, diet & wellness encyclopedia
Jump to navigation Jump to search

AZD2281 A drug used to treat certain types of HER2-negative breast cancer that have spread to other parts of the body.

Clinical use

It is used in patients with certain mutations (changes) in the BRCA1 or BRCA2 genes who have already been treated with other anticancer drugs. It is also used to treat recurrent ovarian epithelial, fallopian tube, or primary peritoneal cancer that has gotten better after treatment with anticancer drugs that included platinum. AZD2281 is also used to treat certain types of advanced ovarian, fallopian tube, or primary peritoneal cancer. It is used in patients with certain mutations in the BRCA1 or BRCA2 genes who have already been treated with other anticancer drugs. It is also being studied in the treatment of other types of cancer.

How does it work?

AZD2281 blocks an enzyme involved in many cell functions, including the repair of DNA damage. Blocking this enzyme may help keep cancer cells from repairing their damaged DNA, causing them to die. AZD2281 is a type of poly (ADP-ribose) polymerase inhibitor.

Other names

Also called Lynparza, olaparib, and PARP inhibitor AZD2281.


Latest research - AZD2281

PubMed
Clinical trials


 

 

AZD2281 is part of WikiMD's free ^articles!

^AZD2281 (article) is provided for informational purposes only. No expressed or implied warranties as to the validity of content.
WikiMD is not a substitute for professional advice. By accessing and using WikiMD you agree to the terms of use.
Templates etc. when imported from Wikipedia, are licensed under CC BY-SA 3.0. See full disclaimers.
W8MD weight loss logo

Ad. Tired of being overweight?. W8MD's physician weight loss program can HELP. Tele medicine available