Acamprosate
Acamprosate
Acamprosate (pronounced as a-kam-pro-sate) is a medication used in the management and treatment of alcohol dependence after detoxification.
Etymology
The term "Acamprosate" is derived from its chemical name: Acetylhomotaurine, camphorsulfonic acid, and propanoic acid.
Definition
Acamprosate is a synthetic compound with a chemical structure similar to that of the endogenous amino acid homotaurine, which is a structural analogue of the amino acid neurotransmitter gamma-aminobutyric acid (GABA). It is used to reduce alcohol cravings in individuals who have stopped drinking alcohol.
Usage
Acamprosate is used along with counseling and social support to help people who have stopped drinking alcohol and are trying to avoid drinking alcohol again. It works by restoring the natural balance of chemicals in the brain (neurotransmitters).
Related Terms
- Alcohol Dependence: A chronic disease characterized by uncontrolled drinking and preoccupation with alcohol.
- Detoxification: The process of removing toxic substances or qualities.
- Neurotransmitter: Chemicals that transmit signals from a neuron to a target cell across a synapse.
- Gamma-aminobutyric acid (GABA): The chief inhibitory neurotransmitter in the mammalian central nervous system.
- Homotaurine: A natural amino acid found in seaweed. It is a precursor of GABA.
Side Effects
Common side effects of Acamprosate include diarrhea, nausea, gas, loss of appetite, and dizziness. A doctor should be consulted if any of these symptoms persist or worsen.
Precautions
Before taking Acamprosate, inform your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems.
External links
- Medical encyclopedia article on Acamprosate
- Wikipedia's article - Acamprosate
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