WikiMD is world's largest health encyclopedia with
28,560 pages, 3,992,028 edits & 34,290,934 views.
Toremifene
Information about Toremifene
Toremifene is a nonsteroidal antiestrogen that is used in the treatment of estrogen receptor positive breast cancer.
Liver safety of Toremifene
Long term toremifene therapy has been associated with development of fatty liver, steatohepatitis, cirrhosis, and rare instances of clinically apparent acute liver injury.
Mechanism of action of Toremifene
Toremifene (tor em' i feen) is a selective estrogen receptor modulator, similar to tamoxifen, that has tissue specific actions with antiestrogenic activity on breast tissue, but estrogenic activity (agonism) on bone and the cardiovascular system.
The antiestrogenic effects of toremifene are the basis for its use in the treatment of estrogen-receptor positive breast cancer. It also has weak estrogenic effects on uterus.
FDA approval information for Toremifene
Toremifene was approved for use in the United States in 1997 and its indications are limited to the treatment of estrogen-receptor positive (or unknown) metastatic breast cancer in postmenopausal women. Unlike tamoxifen, toremifene has not been approved as a means of prevention of de novo breast cancer in high risk patients or for prevention of recurrence of breast cancer.
Dosage and administration for Toremifene
Toremifene is available in tablets of 60 mg under the brand name Fareston. The recommended dose is 60 mg by mouth once daily.
Side effects of Toremifene
Common side effects include hot flashes, sweating, nausea, dizziness, peripheral edema and vaginal discharge. Rare, but potentially severe adverse events include tumor flare (transient worsening soon after starting therapy), prolongation of the QTc interval, venous thrombosis and pulmonary embolism and endometrial (uterine) carcinoma.
Alphabetic list of antineoplastic agents - 0-9 - A1 - A2 - A3 - A4 - A5 -A6 - B - C - D - E - F - G - H - I - JK - L - M - NO - PQ - R - S - T - UVW - XYZ
Cost and Coupons - Toremifene
- GoodRx compare cost & coupons for Toremifene
- Find the lowest cost of Toremifene
- Search for Coupons for Toremifene
Reviews for Toremifene
Learn more about Toremifene
Latest research (Pubmed)
External links
WikiMD needs you!
This WikiMD article Toremifene is a stub.
If you are a healthcare professional familiar with the topic Toremifene, or
A subject matter expert or authority on Toremifene, you can help us.
About | Mission | Paid editors welcome!
| Toremifene is part of WikiMD's Physician reviewed^ articles available 4free, 4all, 4ever! |
|---|
| Medicine: Health - Encyclopedia - Topics - Diseases - Cancer - Rare diseases - Random Page Navigation: Drugs - Wellness - Obesity - Diet - Ketogenic diet - W8MD weight loss diet - Editors: Recently Edited Pages - Alphabetical Order - Sponsors - USMLE The content on or accessible through WikiMD is for informational purposes only. WikiMD is not a substitute for professional medical advice. ^See full Disclaimers |
 Ad. Tired of being overweight?. W8MD's insurance Weight loss program can HELP* |
