Information about Theophylline
Theophylline is a xanthine derivative that induces relaxation of smooth muscle in the bronchial tree causing bronchodilation.
Liver safety of Theophylline
Mechanism of action of Theophylline
Theophylline (thee of' i lin) is an effective bronchodilator and is widely used in treatment of acute attacks of asthma and in chronic management of bronchospasm in patients with asthma and chronic obstructive pulmonary disease.
FDA approval information for Theophylline
Theophylline was approved for use in the United States in 1982 and is available in multiple generic forms for oral and intravenous use.
Dosage and administration for Theophylline
Typical capsule or tablet sizes are 100, 200 and 300 mg. Typical dose regimens are 100 to 300 mg three to four times daily. Syrups are available for use in children. Extended release formulations are also available in sizes of 100 to 600 mg which are typically given twice daily. Dosage is highly individualized. Intravenous formations are available for management of acute asthmatic attacks.
Brand name for Theophylline
Theophylline is marketed under multiple brand names including Asmalix, Elixophyllin, Quibron-T, Respbid, Theobid, Duracaps, and Uniphyl.
Side effects of Theophylline
Common side effects of theophylline include dizziness, headache, insomnia, restlessness, tachycardia, palpitations, flushing, nausea, abdominal discomfort and diaphoresis, largely due to the effects of theophylline on the CNS, heart and muscle tissue.
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Latest research (Pubmed)