Mechanism of action
These agents display potent antitumor properties due to their ability to intercalate into dna and interfere with the function of both the topoisomerase I and topoisomerase II enzymes, thereby inhibiting DNA replication and ultimately, interfering with RNA and protein synthesis.
Up to date info
Latest research - Aclacinomycins
Source: Data courtesy of the U.S. National Library of Medicine. Since the data might have changed, please query MeSH on Aclacinomycins for any updates.