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Aclacinomycins - an oligosaccharide anthracycline antibiotic such as aclarubicin isolated from strains of the bacterium streptomyces galilaeus with potential antineoplastic activity.

Mechanism of action

These agents display potent antitumor properties due to their ability to intercalate into dna and interfere with the function of both the topoisomerase I and topoisomerase II enzymes, thereby inhibiting DNA replication and ultimately, interfering with RNA and protein synthesis.

Up to date info


Latest research - Aclacinomycins

Clinical trials

Source: Data courtesy of the U.S. National Library of Medicine. Since the data might have changed, please query MeSH on Aclacinomycins for any updates.

Latest research - Aclacinomycins

Clinical trials

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