Pagetoid reticulosis
Pagetoid Reticulosis
Pagetoid reticulosis (pronunciation: pah-je-toid ret-ic-u-lo-sis) is a rare form of cutaneous T-cell lymphoma that primarily affects the skin. The term "pagetoid" is derived from the resemblance of the skin lesions to those seen in Paget's disease, while "reticulosis" refers to the net-like pattern of skin involvement.
Definition
Pagetoid reticulosis is characterized by localized or widespread, slowly progressive, scaly or eroded patches and plaques. It is a variant of Mycosis fungoides, which is the most common type of cutaneous T-cell lymphoma.
Symptoms
The main symptom of pagetoid reticulosis is the presence of skin lesions, which can vary in size and appearance. They are typically red, scaly, and may be itchy. The lesions may be localized to one area of the body or may be widespread.
Diagnosis
The diagnosis of pagetoid reticulosis is made based on the clinical presentation and confirmed by a skin biopsy. The biopsy will show a dense infiltration of atypical T-cells in the epidermis, which is a characteristic feature of this condition.
Treatment
Treatment options for pagetoid reticulosis include topical corticosteroids, phototherapy, and systemic therapies such as chemotherapy or immunotherapy in severe cases. The choice of treatment depends on the extent of the disease and the patient's overall health.
Prognosis
The prognosis of pagetoid reticulosis is generally good, especially for localized disease. However, widespread disease can be more difficult to treat and may have a poorer prognosis.
See also
External links
- Medical encyclopedia article on Pagetoid reticulosis
- Wikipedia's article - Pagetoid reticulosis
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