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Activating p110d gene mutation

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Activating p110d gene mutation - a mutation in pik3cd, the gene encoding the p110delta catalytic subunit of pi3k, that results in induction of pi3k signaling. Mutations of this type are associated with immunodeficiency 14 (pasli: activated pi3k-delta syndrome, p110-delta-activating mutation causing senescent t-cells, lymphadenopathy, and immunodeficiency).

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