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Acute myeloid leukemia with myelodysplasia-related changes

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acute myeloid leukemia with myelodysplasia-related changes (uh-KYOOT MY-eh-loyd loo-KEE-mee-uh … MY-eh-loh-dis-PLAY-zhuh-ree-LAY-ted CHAYN-jiz) is a type of acute myeloid leukemia in which at least 20% of a patient’s blood or bone marrow is myeloblasts (immature white blood cells) and the patient has one of the following conditions: 1) has had myelodysplastic syndrome (MDS) or a myelodysplastic/myeloproliferative neoplasm (MDS/MPN) before, 2) cells that have changes in certain chromosomes that are similar to those found in MDS, or 3) at least 50% of the cells (of at least two types of blood cells) are abnormal. Acute myeloid leukemia with myelodysplasia-related changes usually occurs in older adults and has a poor prognosis. Also called AML-MRC.


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