Acylation

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Acylation

Acylation (pronunciation: /aɪˈkleɪʃən/) is a process or reaction that introduces an acyl group into a molecule. The term is derived from the Greek words 'acyl' meaning 'vinegar' and 'ation' meaning 'process'.

Etymology

The term 'acylation' is derived from the root word 'acyl', which is a functional group derived from organic acids. The suffix '-ation' is used to denote a process or action. Therefore, 'acylation' refers to the process of introducing an acyl group into a molecule.

Process

In the process of acylation, an acyl group is transferred from one molecule to another. This is typically achieved through the use of an acylating agent, which is a chemical compound that can donate an acyl group. The process can occur in a variety of chemical reactions, including Friedel-Crafts acylation, acylation of proteins, and acylation of amines.

Related Terms

  • Acyl Group: An organic compound that has a functional group with the structure R-C=O, where R is any organic residue.
  • Acylating Agent: A chemical compound that can donate an acyl group to another molecule.
  • Friedel-Crafts Acylation: A specific type of acylation reaction that involves the use of an acyl chloride and a Lewis acid as a catalyst.
  • Acylation of Proteins: A post-translational modification of proteins that involves the addition of an acyl group.
  • Acylation of Amines: A chemical reaction that involves the addition of an acyl group to an amine.

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