W8MD Diet | COVID-19 portal | Vitamin D | Vaccine | Keto

WikiMD is the world's largest medical encyclopedia with
14,022 pages, 4,158,158 edits & 43,132,019 views.

Free unbiased diet, health and wellness info!

Ad5-hgcc-padre vaccine

From WikiMD's free health, diet & wellness encyclopedia
Jump to navigation Jump to search

Ad5-hgcc-padre vaccine - a replication-defective, recombinant adenoviral serotype 5 (ad5) encoding human guanylyl cyclase c (hgcc) and the synthetic pan dr epitope (padre), with potential antineoplastic and immunomodulating activities. Upon intramuscular administration, the ad5-hgcc-padre vaccine expresses hgcc, which may induce both humoral and cellular immune responses against tumor cells expressing the hgcc antigen. This results in the immune-mediated inhibition of tumor cell proliferation, and leads to tumor death. The hgcc protein is normally restricted to intestinal epithelial cells but is overexpressed by metastatic colorectal tumors. Padre is a helper t-lymphocyte epitope that is able to augment the magnitude and duration of the cytotoxic t-lymphocyte (ctl) response. Also see adenovirus 5-human guanylyl cyclase c-padre vaccine

Up to date info


Latest research - Ad5-hgcc-padre vaccine

Clinical trials

Source: Data courtesy of the U.S. National Library of Medicine. Since the data might have changed, please query MeSH on Ad5-hgcc-padre vaccine for any updates.


Ad5-hgcc-padre vaccine is part of WikiMD's free ^articles!

^Ad5-hgcc-padre vaccine (article) is provided for informational purposes only. No expressed or implied warranties as to the validity of content.
WikiMD is not a substitute for professional advice. By accessing and using WikiMD you agree to the terms of use.
Templates etc. when imported from Wikipedia, are licensed under CC BY-SA 3.0. See full disclaimers.
W8MD weight loss logo

Ad. Tired of being overweight?. W8MD's physician weight loss program can HELP. Tele medicine available