W8MD Diet | COVID-19 portal | Vitamin D | Vaccine | Keto

WikiMD is the world's largest medical encyclopedia with
14,010 pages, 4,159,395 edits & 43,392,504 views.

Free unbiased diet, health and wellness info!

Ad5CMV-p53 gene

From WikiMD's free health, diet & wellness encyclopedia
Jump to navigation Jump to search

A replication-defective adenoviral-CMV vector that encodes a wild-type p53 gene.

Mechanism of action of Ad5CMV-p53 gene

Ad5CMV-p53 induces tumor cells that have been transfected with the vector to produce wild-type p53, a tumor suppressor gene that is deleted or mutated in a significant number of cancers. In transfected tumor cells, the wild-type p-53 gene product exerts an antitumor effect by blocking cell cycle progression at the G1/S regulation point, activating DNA repair proteins in the presence of DNA damage, and initiating apoptosis when DNA damage is irreparable.

Learn more about Ad5CMV-p53 gene

Latest research - Ad5CMV-p53 gene

Clinical trials

External links

Medicine icon
Medicine icon

This WikiMD article Ad5CMV-p53 gene is a stub. If you are familiar with the topic Ad5CMV-p53 gene, you can help us. Paid editors welcome!


Ad5CMV-p53 gene is part of WikiMD's free ^articles!

^Ad5CMV-p53 gene (article) is provided for informational purposes only. No expressed or implied warranties as to the validity of content.
WikiMD is not a substitute for professional advice. By accessing and using WikiMD you agree to the terms of use.
Templates etc. when imported from Wikipedia, are licensed under CC BY-SA 3.0. See full disclaimers.
W8MD weight loss logo

Ad. Tired of being overweight?. W8MD's physician weight loss program can HELP. Tele medicine available