Adeno-associated virus (AAV)
A virus used to construct vectors that introduce genes into cultured cells. Recently, researchers started to use AAV as a convenient vector for expression ofshort hairpin RNA (shRNA)inRNAistudies.
AAV integrates into the host cell genome very inefficiently and appears not to generate immune response, but as a vector it cannot carry large genes. It is potentially useful for "hit and run" gene therapy, where a single burst of therapeutic gene expression is desired.
More about adeno-associated viruses and RNAi inPubMed.
Latest research - Adeno-associated virus (AAV)