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Skeletal formula of aderbasib
Clinical data
Routes of
ATC code
  • None
Legal status
Legal status
  • Investigational
CAS Number
PubChem CID
E number{{#property:P628}}
CompTox Dashboard (EPA)
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Chemical and physical data
Molar mass416.47 g·mol−1 g·mol−1
3D model (JSmol)

Aderbasib (codenamed INCB7839) is a sheddase inhibitor that may suppress tumor cell proliferation.[1] Acting on multiple receptor classes and subclasses, aderbasib is observed to regulate the tumor necrosis factor of cancer cells.[2] Aderbasib was being developed by Incyte as a potential adjunctive treatment for metastatic breast cancer. Development was halted in 2011 after positive findings from Phase II trials were contradicted by further research.[3][4]


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