Mastocytosis
Mastocytosis
Mastocytosis (pronounced mas-to-sy-toe-sis) is a condition that occurs when mast cells, a type of white blood cell, accumulate in skin, bone marrow, and other organs.
Etymology
The term "Mastocytosis" is derived from the Greek words "mastos" meaning "breast" and "kytosis" meaning "cell condition".
Definition
Mastocytosis is a disorder characterized by the excessive accumulation of mast cells in the body's tissues. These cells play a crucial role in the body's immune response, particularly in the production of histamine, a substance involved in allergic reactions.
Types
There are two main types of mastocytosis: cutaneous and systemic.
- Cutaneous Mastocytosis (CM) is confined to the skin and is more common in children.
- Systemic Mastocytosis (SM) affects more than one part of the body and is more common in adults.
Symptoms
Symptoms of mastocytosis can vary widely and can include skin lesions, abdominal discomfort, diarrhea, and anaphylaxis.
Diagnosis
Diagnosis of mastocytosis often involves a physical examination, blood tests, and a bone marrow biopsy.
Treatment
Treatment for mastocytosis is typically aimed at managing symptoms and can include antihistamines, corticosteroids, and other medications.
Prognosis
The prognosis for individuals with mastocytosis can vary greatly depending on the type and severity of the condition.
See Also
External links
- Medical encyclopedia article on Mastocytosis
- Wikipedia's article - Mastocytosis
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