Aflibercept

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Aflibercept

Aflibercept (pronounced as af-li-BER-sept) is a biopharmaceutical drug that is used in the treatment of certain eye diseases and cancer.

Etymology

The name "Aflibercept" is derived from the combination of two words: "Affinity" and "Receptor". It signifies the drug's ability to bind with high affinity to certain receptors in the body.

Usage

Aflibercept is used in the treatment of wet age-related macular degeneration, macular edema following retinal vein occlusion, diabetic macular edema, and diabetic retinopathy. In cancer treatment, it is used in combination with chemotherapy for metastatic colorectal cancer and lung cancer.

Mechanism of Action

Aflibercept works by binding to vascular endothelial growth factor (VEGF) and preventing it from interacting with its receptors on the surface of cells. This inhibits the growth of new blood vessels, which is a key factor in the progression of the diseases it is used to treat.

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