Anaplastic oligodendroglioma

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Anaplastic Oligodendroglioma

Anaplastic oligodendroglioma (pronunciation: an-uh-plas-tik oli-go-den-dro-gli-oma) is a rare type of brain tumor that originates from the oligodendrocytes, a type of cell found in the brain and spinal cord.

Etymology

The term "anaplastic" is derived from the Greek word "anaplasia", meaning "to form backward", referring to the tumor's aggressive nature and tendency to revert to a more primitive or undifferentiated state. "Oligodendroglioma" is derived from "oligo" meaning "few", "dendro" meaning "tree", and "glioma" meaning "glue", referring to the appearance of the cells under a microscope.

Description

Anaplastic oligodendrogliomas are characterized by rapid growth and a high degree of malignancy. They are most commonly found in adults, with a peak incidence in the fourth and fifth decades of life. Symptoms can vary widely depending on the location of the tumor, but may include headache, seizure, and neurological deficits.

Diagnosis

Diagnosis of anaplastic oligodendroglioma typically involves a combination of neurological examination, imaging studies such as MRI or CT scan, and biopsy for histopathological examination.

Treatment

Treatment options for anaplastic oligodendroglioma include surgery, radiation therapy, and chemotherapy. The choice of treatment depends on various factors including the patient's overall health, the size and location of the tumor, and the presence of any genetic mutations.

Prognosis

The prognosis for patients with anaplastic oligodendroglioma is generally poor, with a median survival time of 3 to 5 years. However, survival can vary widely depending on factors such as age, overall health, and response to treatment.

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