Androstane
Androstane
Androstane (pronounced: an-dro-stane) is a steroid hydrocarbon with a formula of C19H32. It is one of the fundamental structures in steroidogenesis and is a precursor to a variety of bioactive steroids, including testosterone and progesterone.
Etymology
The term "Androstane" is derived from the Greek words "Andro" meaning man and "stane" meaning stand. This is in reference to its role in the development of male secondary sexual characteristics.
Structure and Synthesis
Androstane is a 19-carbon steroid that is synthesized from cholesterol in the adrenal glands and gonads. The synthesis involves several enzymatic steps, including the removal of the side chain of cholesterol and the introduction of double bonds to form the androstane structure.
Biological Role
Androstane serves as a precursor to many important steroids in the body. It is converted to androstenedione and dehydroepiandrosterone (DHEA), which are then further converted to testosterone and other androgens. In the female body, androstane derivatives also serve as precursors to estrogens.
Related Terms
- Androgen: A type of hormone that promotes the development and maintenance of male sex characteristics.
- Steroidogenesis: The biological process of producing steroid hormones.
- Testosterone: A steroid hormone from the androgen group and is found in mammals, reptiles, birds, and other vertebrates.
- Progesterone: A type of steroid hormone that plays a crucial role in the menstrual cycle and in maintaining the early stages of pregnancy.
External links
- Medical encyclopedia article on Androstane
- Wikipedia's article - Androstane
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