An antiparkinson, or antiparkinsonian, is a type of drug which is intended to treat and relieve the symptoms of Parkinson's disease (PD) or Parkinsonism. Most of these agents act by either increasing dopamine activity or reducing acetylcholine activity in the central nervous system (CNS).
- Dopaminergic Precursors:
(Preferred over other medications to prevent undesirable sympathomimetic side effects)
- Selective monoamine oxidase B inhibitors
(To prevent the metabolism of dopamine by MAOB and hence increase its brain levels)
- COMT inhibitors
(Preventing the metabolism of dopamine by COMT and hence increase its brain levels)
- Dopamine receptor agonists
(Directly increase the activity of the dopamine system)
- Anticholinergics - Antimuscarinics (e.g., Benzatropine): to prevent hyperkinesia.
|This drug article relating to the nervous system is a stub. You can help Wikipedia by expanding it.|