Antiplatelet agent
Antiplatelet agent
An Antiplatelet agent (pronunciation: an-tee-plate-let ay-gent) is a member of a class of pharmaceuticals that decrease platelet aggregation and inhibit thrombus formation. They are effective in the arterial circulation, where anticoagulants have little effect.
Etymology
The term "Antiplatelet agent" is derived from the Greek words "anti" meaning against, "platelet" which is a small cell fragment in the blood that helps with clotting, and "agent" meaning something that produces an effect.
Mechanism of action
Antiplatelet agents work by inhibiting the enzyme cyclooxygenase, thereby reducing the production of thromboxane. Thromboxane is a substance that stimulates platelet aggregation and promotes vasoconstriction, which can lead to blood clot formation.
Types of Antiplatelet agents
There are several types of antiplatelet agents, including Aspirin, Clopidogrel, Ticlopidine, and Dipyridamole. These drugs are often used in combination to prevent stroke and myocardial infarction.
Side effects
Common side effects of antiplatelet agents include bleeding, bruising, and gastrointestinal upset. In rare cases, these drugs can cause thrombotic thrombocytopenic purpura, a serious condition that results in the formation of small blood clots throughout the body.
See also
External links
- Medical encyclopedia article on Antiplatelet agent
- Wikipedia's article - Antiplatelet agent
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