Asimadoline

From WikiMD.org
Jump to navigation Jump to search

Asimadoline (pronounced as-ee-mad-oh-leen) is a drug that is primarily used in the treatment of Irritable Bowel Syndrome (IBS). It is a kappa opioid receptor agonist, meaning it binds to and activates these receptors in the body.

Etymology

The term "Asimadoline" is derived from the Greek words "Asi" meaning "without" and "madoline" meaning "pain". This is in reference to the drug's primary function as a pain reliever.

Pharmacology

Asimadoline works by binding to the kappa opioid receptors in the gut. This reduces the sensation of pain and discomfort, making it effective in the treatment of IBS. It is a peripherally selective drug, meaning it primarily affects the peripheral nervous system rather than the central nervous system. This reduces the risk of central side effects such as sedation or euphoria.

Clinical Use

Asimadoline is used in the treatment of IBS, particularly in cases where pain and discomfort are the primary symptoms. It has been shown to be effective in reducing these symptoms and improving quality of life for patients with this condition.

Related Terms

See Also

External links

Esculaap.svg

This WikiMD dictionary article is a stub. You can help make it a full article.


Languages: - East Asian 中文, 日本, 한국어, South Asian हिन्दी, Urdu, বাংলা, తెలుగు, தமிழ், ಕನ್ನಡ,
Southeast Asian Indonesian, Vietnamese, Thai, မြန်မာဘာသာ, European español, Deutsch, français, русский, português do Brasil, Italian, polski