BMS-906024
BMS-906024
BMS-906024 (/bɪms naɪn oʊ sɪks oʊ tuː fɔːr/) is a potent and selective gamma-secretase inhibitor that is currently under investigation for its potential therapeutic applications in the treatment of cancer.
Etymology
The term "BMS-906024" is a proprietary designation given by the pharmaceutical company Bristol-Myers Squibb. The "BMS" stands for Bristol-Myers Squibb, while the numerical sequence "906024" is an arbitrary designation used for identification purposes.
Related Terms
- Gamma-secretase: An intramembrane protease that plays a crucial role in cellular processes such as Notch signaling and amyloid precursor protein processing. Inhibition of gamma-secretase is a potential therapeutic strategy in cancer treatment.
- Notch signaling pathway: A highly conserved cell signaling system present in most multicellular organisms. Malfunctions in this pathway can lead to various forms of cancer.
- Amyloid precursor protein: A transmembrane protein that is processed by gamma-secretase. Abnormal processing of this protein is implicated in the development of Alzheimer's disease.
- Bristol-Myers Squibb: A global biopharmaceutical company that is the developer of BMS-906024.
See Also
- Gamma-secretase inhibitor
- Notch signaling pathway
- Amyloid precursor protein
- Alzheimer's disease
- Bristol-Myers Squibb
External links
- Medical encyclopedia article on BMS-906024
- Wikipedia's article - BMS-906024
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