Bamlanivimab

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Bamlanivimab (pronounced bam-lan-iv-im-ab) is a monoclonal antibody developed for the treatment of mild to moderate COVID-19 in adults and pediatric patients. It is specifically designed to block the virus' attachment and entry into human cells.

Etymology

The name "Bamlanivimab" is derived from the following components: "bam" from the company name BioNTech, "lan" for the targeted species (human), "vi" for the disease targeted (virus), "mab" for the product class (monoclonal antibody).

Usage

Bamlanivimab is used in patients with positive results of direct SARS-CoV-2 viral testing, and who are at high risk for progressing to severe COVID-19 and/or hospitalization. It is administered as a single dose intravenously.

Mechanism of Action

Bamlanivimab is a recombinant, neutralizing human IgG1 monoclonal antibody that binds to the spike protein of SARS-CoV-2. It is designed to block viral attachment and entry into human cells, thus neutralizing the virus.

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