Basophil

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Basophil

Basophil (/bæsəfɪl/; from the Greek baso- meaning "base" and -phil meaning "love") is a type of white blood cell that is part of the immune system. Basophils are the least common of the granulocytes, representing about 0.5% to 1% of circulating white blood cells. Despite this, they are important in the body's defense against parasites and play a role in allergic reactions.

Etymology

The term "basophil" comes from the Greek baso- meaning "base" and -phil meaning "love". This is because basophils stain darkly with basic (alkaline) dyes, due to the large amounts of acidic granules stored in their cytoplasm.

Function

Basophils contain large cytoplasmic granules which obscure the cell nucleus under the microscope when stained. These granules contain histamine, heparin, and other chemicals that are released during immune responses. Basophils play a crucial role in the body's defense against parasites, especially parasitic worms. They are also involved in allergic reactions, as the chemicals they release contribute to inflammation and tissue damage.

Related Terms

  • Eosinophil: Another type of granulocyte, which also plays a role in the immune response to parasites and in allergic reactions.
  • Mast cell: A type of immune cell that, like basophils, releases histamine and other chemicals during allergic reactions.
  • Granulocyte: A category of white blood cells that includes basophils, eosinophils, and neutrophils.
  • Leukocyte: The scientific term for white blood cells, which includes basophils.

See Also

External links

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