Bazedoxifene
Bazedoxifene
Bazedoxifene (pronounced ba-zed-ox-i-fene) is a Selective estrogen receptor modulator (SERM) used primarily in the treatment and prevention of osteoporosis in postmenopausal women. It is also used in combination with conjugated estrogens as a treatment for menopausal symptoms.
Etymology
The term "Bazedoxifene" is derived from its chemical structure. The prefix "Baze-" is an arbitrary designation, while "-doxifene" is a common suffix for drugs in the SERM class, indicating their function as estrogen receptor modulators.
Pharmacology
Bazedoxifene acts as an agonist at estrogen receptors in bone tissue, helping to maintain bone density and reduce the risk of fractures. It acts as an antagonist at estrogen receptors in the uterus and breast, reducing the risk of endometrial hyperplasia and breast cancer.
Related Terms
- Selective estrogen receptor modulator (SERM)
- Osteoporosis
- Conjugated estrogens
- Agonist
- Antagonist
- Endometrial hyperplasia
- Breast cancer
See Also
External links
- Medical encyclopedia article on Bazedoxifene
- Wikipedia's article - Bazedoxifene
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