Bazedoxifene

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Bazedoxifene

Bazedoxifene (pronounced ba-zed-ox-i-fene) is a Selective estrogen receptor modulator (SERM) used primarily in the treatment and prevention of osteoporosis in postmenopausal women. It is also used in combination with conjugated estrogens as a treatment for menopausal symptoms.

Etymology

The term "Bazedoxifene" is derived from its chemical structure. The prefix "Baze-" is an arbitrary designation, while "-doxifene" is a common suffix for drugs in the SERM class, indicating their function as estrogen receptor modulators.

Pharmacology

Bazedoxifene acts as an agonist at estrogen receptors in bone tissue, helping to maintain bone density and reduce the risk of fractures. It acts as an antagonist at estrogen receptors in the uterus and breast, reducing the risk of endometrial hyperplasia and breast cancer.

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