Befetupitant

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Befetupitant

Befetupitant (pronunciation: be-fe-tu-pi-tant) is a potent and selective neurokinin 1 receptor antagonist used in the treatment of chemotherapy-induced nausea and vomiting (CINV) and postoperative nausea and vomiting (PONV).

Etymology

The term "Befetupitant" is derived from the combination of its chemical properties and its therapeutic use. "Be" refers to its chemical structure as a benzyl derivative, "fe" signifies its phenyl group, "tu" indicates its therapeutic use as a tachykinin antagonist, and "pitant" is a common suffix for neurokinin 1 receptor antagonists.

Pharmacology

Befetupitant acts by blocking the neurokinin 1 receptor, thus preventing the binding of substance P, a neuropeptide involved in pain perception and the vomiting reflex. By inhibiting the action of substance P, Befetupitant reduces the incidence and severity of nausea and vomiting associated with chemotherapy and surgery.

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