Bendamustine
Bendamustine (pronounced ben-da-MUS-teen) is a chemotherapy drug used in the treatment of certain types of cancer, including chronic lymphocytic leukemia (CLL) and non-Hodgkin lymphoma (NHL).
Etymology
The name "Bendamustine" is derived from the combination of two words: "benzimidazole" and "mustard". The "benzimidazole" part of the name refers to the benzimidazole ring structure found in the compound, while "mustard" refers to the alkylating mustard group, which is responsible for the drug's cytotoxic activity.
Pharmacology
Bendamustine is classified as an alkylating agent, which means it works by damaging the DNA of cancer cells, preventing them from dividing and growing. It is also considered a purine analog, as it interferes with DNA synthesis by mimicking the structure of purine bases.
Usage
Bendamustine is used in the treatment of certain types of cancer, including chronic lymphocytic leukemia and non-Hodgkin lymphoma. It may be used alone or in combination with other chemotherapy drugs.
Side Effects
Like all chemotherapy drugs, Bendamustine can cause side effects. These may include nausea, vomiting, fatigue, and hair loss. More serious side effects can include low blood counts, infection, and infertility.
Related Terms
- Chemotherapy
- Chronic lymphocytic leukemia
- Non-Hodgkin lymphoma
- Alkylating agent
- Purine analog
- Benzimidazole
External links
- Medical encyclopedia article on Bendamustine
- Wikipedia's article - Bendamustine
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