Bentiromide
Bentiromide
Bentiromide (pronunciation: ben-tee-ROH-mide) is a diagnostic agent used in the medical field to evaluate the function of the pancreas.
Etymology
The term "Bentiromide" is derived from its chemical structure, which is composed of p-aminobenzoic acid (PABA) and N-benzoyl-L-tyrosine ethyl ester.
Usage
Bentiromide is primarily used in a test known as the Bentiromide test, which is a non-invasive procedure used to assess the exocrine function of the pancreas. The test is based on the ability of the pancreas to secrete the enzyme Chymotrypsin into the small intestine, which is necessary for the digestion of proteins.
Mechanism of Action
Bentiromide is a compound that is cleaved by chymotrypsin to yield PABA and tyrosine. The amount of PABA excreted in the urine is measured and used as an indicator of pancreatic function. If the pancreas is functioning normally, a high amount of PABA will be detected in the urine. If the pancreas is not functioning properly, a low amount of PABA will be detected.
Related Terms
- Pancreas - A glandular organ in the digestive system and endocrine system of vertebrates.
- Chymotrypsin - A digestive enzyme component of pancreatic juice acting in the small intestine where it performs proteolysis, the breakdown of proteins and polypeptides.
- PABA - Para-Aminobenzoic Acid, a compound that is part of the Bentiromide molecule and is used as a measure of pancreatic function.
See Also
- Pancreatic function test - A set of medical tests designed to evaluate the function of the pancreas.
External links
- Medical encyclopedia article on Bentiromide
- Wikipedia's article - Bentiromide
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