Breyanzi

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Breyanzi
TermBreyanzi
Short definitionBreyanzi - (pronounced) (brey-AN-zee) A drug used to treat adults with certain types of large B-cell lymphoma that have relapsed (returned) or failed to improve after treatment with at least one systemic therapy. It is also being studied in the treatment of other types of cancer. 
TypeCancer terms
SpecialtyOncology
LanguageEnglish
SourceNCI
Comments


Breyanzi - (pronounced) (brey-AN-zee) A drug used to treat adults with certain types of large B-cell lymphoma that have relapsed (returned) or failed to improve after treatment with at least one systemic therapy. It is also being studied in the treatment of other types of cancer. Breyanzi is made using a patient's T cells (a type of cell in the immune system). A gene for a special receptor called the chimeric antigen receptor (CAR) is added to the T cells in the laboratory. Large numbers of these modified T cells, known as CAR T cells, are cultivated in the laboratory and given to the patient by infusion. Breyanzi attaches to a protein called CD19, which is found on most B-cell lymphoma cells. This helps the body's immune system kill cancer cells. Breyanzi is a form of CAR T cell therapy. Also called lisocabtagene maraleucel

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