Budd-Chiari syndrome

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Budd-Chiari syndrome

Budd-Chiari syndrome (pronounced: bud-kee-ah-ree sin-drome) is a rare medical condition that occurs when blood clots block the veins that carry blood from the liver (hepatic veins). The blockage can cause liver damage, and lead to serious complications such as liver failure and cirrhosis.

Etymology

The syndrome is named after the British physician, George Budd, and the Italian pathologist, Hans Chiari, who first described the condition in the 19th century.

Symptoms

The symptoms of Budd-Chiari syndrome can vary, but often include abdominal pain, jaundice, and ascites (fluid build-up in the abdomen). Other symptoms can include fatigue, nausea, and vomiting.

Causes

Budd-Chiari syndrome can be caused by a variety of conditions that can lead to blood clotting, including polycythemia vera, paroxysmal nocturnal hemoglobinuria, and pregnancy. It can also be caused by liver cancer or liver cirrhosis.

Diagnosis

Diagnosis of Budd-Chiari syndrome often involves a combination of blood tests, imaging tests, and sometimes a liver biopsy.

Treatment

Treatment for Budd-Chiari syndrome depends on the underlying cause of the condition, but can include anticoagulant therapy, thrombolytic therapy, and in severe cases, liver transplantation.

See also

References

External links

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