Buruli ulcer

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Buruli Ulcer

Buruli ulcer (pronounced: bur-oo-lee ul-ser) is a chronic, necrotizing disease of the skin and soft tissues. It is caused by the bacterium Mycobacterium ulcerans and is characterized by the development of painless nodules that can progress to massive skin ulcers if not treated early.

Etymology

The term "Buruli" comes from the Buruli County in Uganda, where the disease was first described in the 1960s. The word "ulcer" is derived from the Latin "ulcus", which means a sore that is open and slow to heal.

Symptoms

The first sign of Buruli ulcer is usually a painless, non-tender nodule (swelling), plaque (raised or thickened patch of skin), or edema (swelling) that can be mistaken for an insect bite. Over time, the nodule can ulcerate (form an ulcer) and the skin around it may die and peel off. The ulcer is typically painless and can be accompanied by bone damage and permanent disfigurement and disability if not treated early.

Treatment

Treatment for Buruli ulcer involves a combination of antibiotics and surgery to remove the affected tissue. The World Health Organization recommends a combination of rifampicin and streptomycin for eight weeks as the first-line treatment.

Prevention

Prevention strategies for Buruli ulcer include avoiding contact with stagnant or slow-flowing water, wearing protective clothing, and promptly cleaning and covering any skin wounds.

Related Terms

External links

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