Captopril challenge test

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Captopril Challenge Test

The Captopril Challenge Test (pronounced: cap-toe-pril) is a diagnostic procedure used primarily in the field of Nephrology and Cardiology to identify Renovascular Hypertension, a condition characterized by high blood pressure due to narrowing of the blood vessels (arteries) that carry blood to the kidneys.

Etymology

The term "Captopril Challenge Test" derives its name from the drug Captopril, an Angiotensin-Converting Enzyme (ACE) Inhibitor used in the test, and the word "challenge", which in medical parlance refers to the administration of a substance to determine if the body's response is normal or not.

Procedure

The Captopril Challenge Test involves the administration of Captopril to a patient, followed by measurements of the patient's blood pressure and levels of certain hormones in the blood, such as Renin and Aldosterone. These measurements are compared before and after the administration of Captopril. An abnormal increase in these levels following the administration of Captopril may indicate the presence of Renovascular Hypertension.

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