Ceftobiprole
Ceftobiprole
Ceftobiprole (pronounced as sef-toe-BIP-role) is an advanced-generation cephalosporin antibiotic that is particularly effective against methicillin-resistant Staphylococcus aureus (MRSA) and Pseudomonas aeruginosa.
Etymology
The term "Ceftobiprole" is derived from "cef-", referring to its class as a cephalosporin antibiotic, and "-biprole", a unique suffix assigned to this specific drug.
Usage
Ceftobiprole is used for the treatment of a variety of bacterial infections, including skin and skin structure infections (SSSIs) and pneumonia. It is especially useful in treating infections caused by MRSA and Pseudomonas aeruginosa, two types of bacteria that are often resistant to other antibiotics.
Mechanism of Action
Ceftobiprole works by inhibiting the synthesis of the bacterial cell wall, leading to cell death. It binds to penicillin-binding proteins (PBPs) on the bacterial cell wall and inhibits the cross-linking of peptidoglycan, a critical component of the bacterial cell wall.
Side Effects
Common side effects of Ceftobiprole include nausea, vomiting, diarrhea, and rash. More serious side effects can include Clostridium difficile-associated diarrhea (CDAD) and allergic reactions.
Related Terms
- Cephalosporin: A class of antibiotics to which Ceftobiprole belongs.
- Methicillin-resistant Staphylococcus aureus (MRSA): A type of bacteria that is resistant to many antibiotics and can be effectively treated with Ceftobiprole.
- Pseudomonas aeruginosa: A type of bacteria that can cause serious infections and can be effectively treated with Ceftobiprole.
- Penicillin-binding proteins (PBPs): Proteins on the bacterial cell wall that Ceftobiprole binds to in order to inhibit cell wall synthesis.
External links
- Medical encyclopedia article on Ceftobiprole
- Wikipedia's article - Ceftobiprole
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