Chemokine receptor

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Chemokine receptor

Chemokine receptors are a type of G protein-coupled receptor that specifically bind and respond to chemokines.

Pronunciation

  • IPA: /ˈkiːmoʊkaɪn rɪˈsɛptər/

Etymology

The term "chemokine receptor" is derived from the words "chemotactic cytokine receptor". "Chemotactic" refers to the ability to direct cell movement, "cytokine" is a type of protein that can influence the immune system, and "receptor" refers to a protein molecule that receives chemical signals from outside a cell.

Function

Chemokine receptors are integral membrane proteins that respond to a type of cytokine known as a chemokine. The interaction of chemokines and their receptors results in a chemotactic response, guiding the migration of cells. They play crucial roles in the immune system, including the development, homeostasis, and function of the immune system.

Types

There are approximately 20 different types of chemokine receptors, which are found on the surface of various types of immune cells. Some of the most well-known chemokine receptors include CCR5, CXCR4, and CX3CR1.

Related Terms

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