Chondromyxoid fibroma

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Chondromyxoid fibroma (pronunciation: kon-dro-mik-soid fy-bro-ma) is a rare, benign bone tumor that typically occurs in the long bones of the legs, but can also occur in the bones of the hands, feet, spine, or flat bones such as the pelvis or skull.

Etymology

The term "Chondromyxoid fibroma" is derived from the Greek words chondros (cartilage), myxos (mucus), and oma (tumor), reflecting the tumor's cartilaginous and myxoid (mucus-like) appearance.

Clinical Presentation

Patients with Chondromyxoid fibroma often present with pain or swelling in the affected area. The tumor may also be discovered incidentally during imaging studies for unrelated conditions.

Diagnosis

Diagnosis of Chondromyxoid fibroma is typically made through a combination of radiographic imaging and histopathological examination. The tumor often appears as a well-defined, lytic lesion on radiographs. Histologically, the tumor is characterized by a lobulated pattern of chondroid and myxoid tissue, with spindle-shaped cells and multinucleated giant cells.

Treatment

Treatment for Chondromyxoid fibroma typically involves surgical removal of the tumor. In some cases, curettage (scraping out the tumor) may be sufficient, while in other cases, more extensive surgery may be required.

Prognosis

The prognosis for Chondromyxoid fibroma is generally good, with a low rate of recurrence following complete surgical removal. However, the tumor can be locally aggressive and may cause significant morbidity if not treated promptly.

Related Terms

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