Logo


W8MD Diet | COVID-19 portal | Vitamin D | Vaccine | Keto

WikiMD is the world's largest medical encyclopedia with
29,037 pages, 4,107,582 edits & 35,762,818 views.

Free unbiased diet, health and wellness info!

Phototrexate

From WikiMD's free health, diet & wellness encyclopedia
(Redirected from Cis-phototrexate)
Jump to navigation Jump to search
trans-Phototrexate
Phototrexate skeletal.svg
Clinical data
ATC code
  • None
Identifiers
E number{{#property:P628}}
CompTox Dashboard (EPA)
  • {{#property:P3117}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
ECHA InfoCard{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
FormulaC20H19N7O5
Molar mass g·mol−1
3D model (JSmol)

Phototrexate is a photopharmacological agent[1][2] that behaves as light-regulated inhibitor of the dihydrofolate reductase (DHFR).[3][4] It is a photoisomerizable structural analogue of the chemotherapy agent methotrexate. Pharmacological effects of phototrexate can be switched on and off by UVA and visible light, respectively. Phototrexate is almost inactive in its trans configuration while it behaves as a potent antifolate in its cis configuration. It can also spontaneously self-deactivate in the dark.

cis-Phototrexate

See also

References


edit 

WikiMD Resources - Phototrexate

Latest research (Pubmed)

PubMed


Join WikiMD as a freelancer or paid editor and help improve the page Phototrexate or others.
Phototrexate is part of WikiMD's Physician reviewed^ articles available 4free, 4all, 4ever!
Medicine: Health - Encyclopedia‏‎‏‎ - Topics‏‎ -‏‎ Diseases‏‎ - Cancer - Rare diseases - Random Page Navigation: Drugs - Wellness - Obesity‏‎ - Diet - Ketogenic diet - W8MD weight loss diet - Editors: Recently Edited Pages - Alphabetical Order - Sponsors - USMLE The content on or accessible through WikiMD is for informational purposes only. WikiMD is not a substitute for professional medical advice. ^See full Disclaimers
W8MD weight loss logo

Ad. Tired of being overweight?. W8MD's physician weight loss program can HELP*
Special: W8MD's tele-weight loss consultations only $99.99. Call 718-946-5500. Limited acceptance.