Class ii ap endonuclease
Class ii ap endonuclease - apurinic/apyrimidinic (ap) sites occur frequently in dna molecules by spontaneous hydrolysis, by dna damaging agents or by dna glycosylases that remove specific abnormal bases. Ap sites are pre mutagenic lesions that can prevent normal dna replication so the cell contains systems to identify and repair such sites. Class ii ap endonucleases cleave the phosphodiester backbone 5' to the ap site. (from locuslink 27301)
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Source: Data courtesy of the U.S. National Library of Medicine. Since the data might have changed, please query MeSH on Class ii ap endonuclease for any updates.